Try the questions in the test above first, then open each one here to see the correct answer and why every other option is wrong.
01A 52-year-old woman undergoes staging surgery for a suspected epithelial ovarian malignancy. Based on the normal lymphatic pathway of the ovary, which nodal group must be assessed because it receives direct drainage along the ovarian vessels?
Practice question Unit: Anatomy
ASuperficial inguinal nodes below the inguinal ligament
Superficial inguinal nodes drain the vulva and lower vagina, not the ovary.
BPresacral nodes in front of the lower sacrum
Presacral nodes receive drainage mainly from the cervix and rectum via the uterosacral ligaments.
CDeep inguinal nodes medial to the femoral vein
Deep inguinal nodes receive lymph from the superficial inguinal nodes and the clitoris, not directly from the ovary.
DPara-aortic nodes at the level of the renal vessels ✓ Correct answer
Ovarian lymphatics follow the ovarian vessels in the infundibulopelvic ligament to the para-aortic nodes, so isolated high nodal spread is possible.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 1: Anatomy, p. 2; Berek and Hacker's Gynecologic Oncology, chapter: Epithelial Ovarian Cancer
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02A resident assisting at an abdominal hysterectomy is asked to identify the dense condensation of connective tissue at the base of the broad ligament that attaches the cervix and upper vagina to the lateral pelvic wall and carries the uterine vessels. Which structure is this?
Practice question Unit: Anatomy
ARound ligament of the uterus
The round ligament runs from the uterine cornu to the inguinal canal and gives little support.
BCardinal ligament ✓ Correct answer
The cardinal ligament is the main lateral support of the cervix and vaginal apex and transmits the uterine vessels.
CInfundibulopelvic ligament
The infundibulopelvic ligament carries the ovarian vessels from the pelvic brim to the ovary.
DUtero-ovarian ligament
The utero-ovarian ligament joins the ovary to the uterine cornu, far above the cervix.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 1: Anatomy, p. 2; Williams Gynecology, chapter: Anatomy
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03After one sperm fuses with the oocyte, what mechanism normally prevents entry of further sperm?
Practice question Unit: Embryology/Genetics
ALoss of the corona radiata cells by tubal enzymes
Dispersal of corona cells helps sperm reach the zona rather than blocking them.
BAcrosome reaction occurring in the oocyte cytoplasm
The acrosome reaction is a sperm event that enables penetration; it does not block polyspermy.
CCompletion of the first meiotic division at ovulation
Meiosis I completes before ovulation; meiosis II completes at fertilisation, neither blocks polyspermy.
DCortical granule release altering the zona pellucida ✓ Correct answer
Cortical granule exocytosis modifies zona proteins (the zona reaction) so other sperm cannot bind or penetrate.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 2: Embryology/Genetics, p. 2; Williams Obstetrics, chapter: Implantation and Placental Development
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04A healthy woman at 30 weeks has haemoglobin 108 g/L with normal ferritin and MCV. Which physiological change explains this?
Practice question Unit: Physiology
ARed cell mass falls in the second trimester
Red cell mass increases rather than falls.
BPlasma volume rises more than red cell mass ✓ Correct answer
Plasma volume expands by about 40–50% while red cell mass rises by about 20–30%, causing dilutional anaemia.
CFetal uptake of maternal iron exceeds intake
Normal ferritin and MCV argue against iron depletion.
DErythropoietin production is suppressed
Erythropoietin rises in pregnancy.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 3: Physiology, p. 2; Williams Obstetrics, chapter: Maternal Physiology
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05Which enzyme converts pregnenolone to progesterone and DHEA to androstenedione?
Practice question Unit: Biochemistry
A17β-hydroxysteroid dehydrogenase
17β-HSD interconverts androstenedione and testosterone, and oestrone and oestradiol.
B3β-hydroxysteroid dehydrogenase ✓ Correct answer
3β-HSD converts Δ5 steroids to Δ4 steroids, a step needed for every active steroid class.
C21-hydroxylase
21-hydroxylase acts on progesterone and 17-hydroxyprogesterone.
DAromatase
Aromatase converts androgens to oestrogens.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 4: Biochemistry, p. 2; Speroff's Clinical Gynecologic Endocrinology and Infertility, chapter: Hormone Biosynthesis, Metabolism, and Mechanism of Action
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06A 22-year-old woman with acne starts a combined pill with ethinylestradiol. After 4 months her acne has improved. Which hepatic effect of the oestrogen contributes most?
Practice question Unit: Pharmacology
ALower albumin, which raises free testosterone
Albumin changes are minor, and a rise in free testosterone would worsen acne.
BLower cortisol-binding globulin, which lowers cortisol
Oestrogen raises, not lowers, cortisol-binding globulin, and this does not explain acne.
CHigher SHBG, which lowers free testosterone ✓ Correct answer
Ethinylestradiol raises sex hormone-binding globulin, binding testosterone and reducing androgen effects on the skin.
DHigher hepatic 5α-reductase activity
More 5α-reductase would increase dihydrotestosterone and worsen acne.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 5: Pharmacology, p. 2; Williams Obstetrics, chapter: Contraception
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07A 22-year-old has a 6 cm ovarian cyst. Ultrasound shows a hyperechoic nodule with acoustic shadowing and fat-fluid level. What is the likely diagnosis?
Practice question Unit: Pathology/Histology
AMature cystic teratoma ✓ Correct answer
A Rokitansky nodule with shadowing and fat signals a dermoid cyst.
BEndometrioma
Endometriomas have uniform ground-glass echoes.
CHaemorrhagic corpus luteum
Haemorrhagic cysts show a lace-like pattern and resolve.
DMucinous cystadenoma
Mucinous tumours are large and multilocular.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 6: Pathology/Histology, p. 2; Williams Gynecology, chapter: Pelvic Mass
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08A woman has a thin grey vaginal discharge with a fishy odour. Vaginal pH is 5.0 and microscopy shows clue cells. What is the diagnosis?
Practice question Unit: Microbiology/Immunology
ATrichomoniasis
Trichomonas shows motile flagellated organisms and frothy discharge.
BAtrophic vaginitis
Atrophic vaginitis occurs with low oestrogen and lacks clue cells.
CBacterial vaginosis ✓ Correct answer
Amsel criteria: thin discharge, pH over 4.5, fishy amine odour and clue cells.
DVulvovaginal candidiasis
Candida gives thick white discharge with normal pH.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 7: Microbiology/Immunology, p. 2; Williams Gynecology, chapter: Gynecologic Infection
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09On about which day after fertilisation does the blastocyst begin to implant?
Practice question Unit: Endocrinology & Reproduction
ADay 1 to 2
On days 1-2 the zygote is cleaving in the tube.
BDay 3 to 4
On days 3-4 the morula is entering the uterine cavity.
CDay 14 to 15
By day 14 implantation is complete and gastrulation is starting.
DDay 6 to 7 ✓ Correct answer
The blastocyst hatches and begins attaching to the endometrium on days 6-7.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 8: Endocrinology & Reproduction, p. 2; Speroff's Clinical Gynecologic Endocrinology and Infertility, chapter: Sperm and Egg Transport, Fertilization, and Implantation
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10Which fetal shunt directs well-oxygenated inferior vena cava blood from the right atrium to the left atrium?
Practice question Unit: Normal Pregnancy (Fetal/Placental/Parturition)
AForamen ovale ✓ Correct answer
The crista dividens steers IVC blood through the foramen ovale to the left heart and brain.
BDuctus arteriosus
The ductus arteriosus connects pulmonary artery to aorta, bypassing the lungs.
CUmbilical ring
The umbilical ring is an abdominal wall opening, not a cardiac shunt.
DDuctus venosus
The ductus venosus carries umbilical venous blood past the liver to the IVC.
Reference: SCFHS Saudi Board Part One Exam Blueprint – Obstetrics & Gynecology (24-27, v.1), Section 9: Normal Pregnancy (Fetal/Placental/Parturition), p. 2; Williams Obstetrics, chapter: Embryogenesis and Fetal Development
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